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What is the influence of genotype on the success of treatment for chronic hepatitis B?

Nature Clinical Practice Gastroenterology & Hepatology volume 3, pages 620–621 (2006)Cite this article

boxed-textFlink HJ et al. (2006) Treatment with Peg-interferon alpha-2b for HBeAg-positive chronic hepatitis B: HBsAg loss is associated with HBV genotype. Am J Gastroenterol 101: 297–303

Hepatitis B virus genotype A seems to influence response rate to interferon-based treatment; genotype should be included in therapeutic decision-making alongside factors such as age, aminotransferase level, and viral load

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Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

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  1. Professor of Gastroenterology and Hepatology at the Department of Gastroenterology, Hepatology and Endocrinology, and an attending transplant hepatologist at the Hannover Medical School, Germany

    Christian P Strassburg

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  1. Christian P Strassburg
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Correspondence to Christian P Strassburg.

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Strassburg, C. What is the influence of genotype on the success of treatment for chronic hepatitis B?. Nat Rev Gastroenterol Hepatol 3, 620–621 (2006). https://doi.org/10.1038/ncpgasthep0628

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