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Does Helicobacter pylori infection and its eradication have any effect on heartburn and gastroesophageal reflux?

Nature Clinical Practice Gastroenterology & Hepatology volume 1, pages 16–17 (2004)Cite this article

boxed-textHarvey RF et al. (2004) Randomised controlled trial of effects of Helicobacter pylori infection and its eradication on heartburn and gastro-oesophageal reflux: Bristol helicobacter project. BMJ 328: 1417–1419

H. pylori eradication therapy should not be avoided because of fears that it will precipitate or worsen GER

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References

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Acknowledgements

The synopsis was written by Waheed Bhatti, Assistant Editor, Nature Clinical Practice.

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Authors and Affiliations

  1. Associate Professor of Division of Gastroenterology, Medicine and Chief of Clinical Service, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada

    David Armstrong

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  1. David Armstrong
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Correspondence to David Armstrong.

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Glossary

13C-UREA BREATH TEST

Non-invasive test of H. pylori infection; H. pylori urease hydrolyses 13-Clabeled urea to produce labeled 13CO2 that is detected in exhaled breath

CLARITHROMYCIN

Macrolide antibiotic used with a PPI and a second antibiotic or with ranitidine bismuth citrate for H. pylori eradication

RANITIDINE BISMUTH CITRATE

An acid suppressant (ranitidine) and an antimicrobial (bismuth citrate) used, often in combination, with an antibiotic for H. pylori eradication

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Armstrong, D. Does Helicobacter pylori infection and its eradication have any effect on heartburn and gastroesophageal reflux?. Nat Rev Gastroenterol Hepatol 1, 16–17 (2004). https://doi.org/10.1038/ncpgasthep0004

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