Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

Can acute administration of pamidronate help to preserve bone mass in children with severe burn injury?

Nature Clinical Practice Endocrinology & Metabolism volume 4, pages 134–135 (2008)Cite this article

boxed-textPrzkora R et al. (2007) Pamidronate preserves bone mass for at least 2 years following acute administration for pediatric burn injury. Bone 41: 297–302

Pamidronate can prevent bone loss in pediatric patients in the year after a burn; however, before such treatment becomes routine, a positive long-term risk–benefit ratio and effect on peak bone mass will need to be demonstrated

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Klein GL et al. (2005) The efficacy of acute administration of pamidronate on the conservation of bone mass following severe burn injury in children: a double-blind, randomized, controlled study. Osteoporos Int 16: 631–635

    Article  CAS  PubMed  Google Scholar 

  2. Edelman LS et al. (2003) Sustained bone mineral density changes after burn injury. J Surg Res 114: 172–178

    Article  PubMed  Google Scholar 

  3. Bachrach LK (2007) Consensus and controversy regarding osteoporosis in the pediatric population. Endocr Pract 13: 513–520

    Article  PubMed  Google Scholar 

  4. Batch JA et al. (2003) Use of bisphosphonate therapy for osteoporosis in childhood and adolescence. J Paediatr Child Health 39: 88–92

    Article  CAS  PubMed  Google Scholar 

  5. Gafni RI and Baron J (2007) Childhood bone mass acquisition and peak bone mass may not be important determinants of bone mass in late adulthood. Pediatrics 119 (Suppl 2): S131–S136

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice.

Author information

Author notes

  1. Division of Genetics, Enders 5, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA ingrid.holm@childrens.harvard.edu

Authors and Affiliations

  1. IA Holm is an Assistant Professor of Pediatrics at Harvard Medical School and in the Divisions of Genetics and Endocrinology, Children's Hospital, Boston, MA, USA.,

    Ingrid A Holm

Authors
  1. Ingrid A Holm
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Holm, I. Can acute administration of pamidronate help to preserve bone mass in children with severe burn injury?. Nat Rev Endocrinol 4, 134–135 (2008). https://doi.org/10.1038/ncpendmet0724

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpendmet0724

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing