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Rheumatic fever: the potential advantages of technology

Abstract

This article sets out the clinical context of the research presented by Carapetis et al. in an accompanying article in this issue. No screening guidelines exist for early detection of rheumatic heart disease (RHD). The lack of agreed diagnostic criteria is one of the reasons why large proportions of cases in resource poor nations go untreated and are detected only when the disease has progressed to cardiac failure. Here, Poole-Wilson and Seth discuss the study carried out by Jonathan Carapetis and colleagues—a cross-sectional screening protocol in Tongan primary school children. The protocol designed by Carapetis et al. identified the highest echocardiographically confirmed prevalence of RHD reported to date. Poole-Wilson and Seth explore how modern technology, in the shape of portable echocardiography, can help to move the focus on rheumatic heart disease away from epidemiology and crude preventive programs, and towards screening programs that can effectively identify people who should receive treatment before cardiac failure occurs.

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References

  1. Bisno A et al. (2001) Rheumatic fever and rheumatic heart disease: report of a WHO Expert Consultation, Geneva, 29 October to 1 November 2001. WHO Technical Report Series, 923

  2. Guilherme L and Kalil J (2007) Rheumatic fever: from innate to acquired immune response. Ann N Y Acad Sci 1107: 426–433

    Article  CAS  Google Scholar 

  3. Carapetis J et al. (2005) Acute rheumatic fever. Lancet 366: 155–168

    Article  Google Scholar 

  4. Bchir A et al. (2006) Better health statistics are possible. Lancet 367: 190–193

    Article  Google Scholar 

  5. Marijon E et al. (2007) Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med 357: 470–476

    Article  CAS  Google Scholar 

  6. Carapetis et al. (2008) Evaluation of a screening protocol using auscultation and portable echocardiography to detect asymptomatic rheumatic heart disease in Tongan schoolchildren. Nat Clin Pract Cardiovasc Med [10.1038/ncpcardio1185]

  7. Marmot M (2006) Health in an unequal world: social circumstances, biology and disease. Clin Med 6: 559–572

    Article  Google Scholar 

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Correspondence to Philip A Poole-Wilson.

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The authors declare no competing financial interests.

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Poole-Wilson, P., Seth, S. Rheumatic fever: the potential advantages of technology. Nat Rev Cardiol 5, 426–427 (2008). https://doi.org/10.1038/ncpcardio1216

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