Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Case Study
  • Published:

Intracardiac leiomyomatosis: iliac vein to right-ventricular outflow tract

Nature Clinical Practice Cardiovascular Medicine volume 2, pages 369–372 (2005)Cite this article

Abstract

Background A 58-year-old female with a history of hypertension and asthma presented to an internist for a routine physical examination. A grade II/VI systolic ejection murmur and electrocardiogram abnormalities were noted. She was referred to a cardiologist for further assessment.

Investigations Transthoracic echocardiography, transesophageal echocardiography, contrast-enhanced CT and MRI, exploratory laparotomy.

Diagnosis Intracardiac leiomyomatosis.

Management Surgical excision.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Transesophageal echocardiogram.
Figure 2: Gross pathologic specimen of leiomyoma measuring 30.0 cm in length, with a diameter ranging from 1.5 to 2.5 cm.
Figure 3: Microscopic examination of leiomyoma with focal hyalinization and myxoid degeneration.

References

  1. Gopal AS et al. (2001) Differential diagnosis of intracavitary tumors obstructing the right ventricular outflow tract. J Am Soc Echocardiogr 14: 937–940

    Article  CAS  Google Scholar 

  2. Goldman A et al. (1985) Renal cell carcinoma and right atrial tumor diagnosed by echocardiography. Am Heart J 110 (Pt 1): 183–186

    Article  Google Scholar 

  3. Farooki ZQ et al. (1975) Echocardiographic diagnosis of right atrial extension of Wilms' tumor. Am J Cardiol 36: 363–365

    Article  CAS  Google Scholar 

  4. Gonzalez-Lavin L et al. (1984) Tricuspid valve obstruction due to intravenous leiomyomatosis. Am Heart J 108: 1544–1546

    Article  CAS  Google Scholar 

  5. Hayasaka K et al. (2000) Intravenous leiomyomatosis. J Comput Assist Tomogr 24: 83–85

    Article  CAS  Google Scholar 

  6. Lam PM et al. (2004) Intravenous leimyomatosis: two cases with different routes of tumor extension. J Vasc Surg 39: 465–469

    Article  Google Scholar 

  7. Steinmetz OK et al. (1996) Uterine tumor in the heart: intravenous leiomyomatosis. Surgery 119: 226–229

    Article  CAS  Google Scholar 

  8. Matsumoto K et al. (1994) Intravenous leiomyomatosis of the uterus. Eur J Vasc Surg 8: 377–378

    Article  CAS  Google Scholar 

  9. Bahary CM et al. (1982) Intravascular leiomyomatosis. Obstet Gyncol 59 (Suppl): 73S–77S

    CAS  Google Scholar 

  10. Roques F et al. (2001) Role of pre-operative assessment in the surgical management of leiomyoma extended to the right heart chambers: a compendium of information from isolated reports. Eur J Cardiothorac Surg 19: 522–524

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Internal Medicine,

    Edward S Bennett, Timothy T Robinson & Icilma Fergus

  2. Kyrenia Cardiac Center, Flushing, NY, USA

    Edward S Bennett, Timothy T Robinson & Icilma Fergus

  3. Junior Resident in Internal Medicine at Tripler Medical Center, Honolulu, HI, USA

    Navin S Arora

  4. Attending Cardiologist of the Cardiovascular Associates, Bayside, NY, USA

    Martin Kay

Authors
  1. Edward S Bennett
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Navin S Arora
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Martin Kay
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Timothy T Robinson
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Icilma Fergus
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Icilma Fergus.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bennett, E., Arora, N., Kay, M. et al. Intracardiac leiomyomatosis: iliac vein to right-ventricular outflow tract. Nat Rev Cardiol 2, 369–372 (2005). https://doi.org/10.1038/ncpcardio0250

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpcardio0250

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing