Figure 7: The in vivo effect of cholesterol depletion on tactile allodynia of STOML3−/− mice. | Nature Communications

Figure 7: The in vivo effect of cholesterol depletion on tactile allodynia of STOML3−/− mice.

From: Membrane stiffening by STOML3 facilitates mechanosensation in sensory neurons

Figure 7

MβCD presented an analgesic effect on nerve injury-induced tactile allodynia in C57BL/6N, but not in STOML3−/− mice (n=6–12 mice per group, MβCD effect: one-way ANOVA with post hoc Bonferroni’s multiple comparison test, C57BL/6N: ipsilateral, P<0.05; contralateral, P>0.05; STOML3−/−: ipsilateral, P>0.05; contralateral, P>0.05; STOML3 influence: C57BL/6N versus STOML3−/−, two-way repeated measures ANOVA with post hoc Bonferroni’s test, P<0.001). *P<0.05, **P<0.01, ****P<0.0001. Error bars indicate s.e.m.

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