Figure 4: AFM-infrared chemical maps and spectra after 2-day incubation. | Nature Communications

Figure 4: AFM-infrared chemical maps and spectra after 2-day incubation.

From: Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Figure 4

(a) AFM height image. Infrared absorption in amide I (b) and at (c) 1,700 cm−1 and (d) 1,655 cm−1. Scale bar, 2 μm. (d) Spectra of misfolded oligomers, which are native-like with amide I similar to the monomeric structures. (e) Spectra of misfolded oligomers, fibril-like showing a conformational switch towards β-sheet structure.

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