Figure 7 : An H3K36 chromatin switch regulates DSB repair pathway choice in fission yeast.

From: A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice

Figure 7

In G1 high levels of Set2-dependent H3K36me (indicated) reduces nucleosome accessibility to repair factors, resulting in reduced resection and increased NHEJ repair of DSBs. In S/G2 high levels of Gcn5-dependent H3K36Ac (indicated) increases nucleosome accessibility to repair factors,resulting in increased resection and increased HR repair of DSBs. See text for details.