Figure 1: Effects of CI-III on BDNF-induced changes in levels of SCOP and p-ERK. | Nature Communications

Figure 1: Effects of CI-III on BDNF-induced changes in levels of SCOP and p-ERK.

From: A molecular brake controls the magnitude of long-term potentiation

Figure 1

(a,d,g) Experimental protocols: hippocampal slices were prepared from adult rats and were treated with BDNF (100 ng ml−1) for the indicated periods of time in the absence or presence of CI-III (10 μM), as indicated. (b,e,h) Representative western blots for SCOP, Akt, p-ERK and ERK under various experimental conditions. (c,f,i) Quantitative analysis of the levels of SCOP (normalized to the values of Akt) and p-ERK/ERK ratios under various experimental conditions. In all cases, results are means±s.e.m. of three experiments. *P<0.05, as compared with time point 0, one-way analysis of variance followed by Bonferroni test.

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