Figure 6 : Novel gene mutations identified in multiple myeloma.

From: Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

Figure 6

Schematic representation of known or predicted functional domains (from NCBI) of the protein products of the main novel genes identified in the screen, and location of the observed variants, color coded by type: red=truncating variants (nonsense, out-of-frame indels, essential splice-site mutations), green=missense variants, and blue=in-frame indels. FAT3 shows a homozygous deletion spanning the whole locus in a patient and this is shown by a red bar.