Figure 3: Inflammation and tissue pathology in the caecum following chronic infection with AIEC. | Nature Communications

Figure 3: Inflammation and tissue pathology in the caecum following chronic infection with AIEC.

From: Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis

Figure 3

(a) Haematoxylin and eosin staining of caecal sections from CD1, DBA/2, 129e, C3H and C57BL/6 mice after AIEC infection, and from uninfected controls. Images are representative of two experiments with four mice per time point. MM, muscularis mucosa; SM, submucosa; M, mucosa; L, lumen. Arrows indicate submucosa oedema, desquamation, hyperplasia, inflammatory cellular infiltrates and epithelial sloughing. (b) Caecal pathology was scored 3 weeks after infection. Scores represent an average of five views per section, and data are expressed as the means with s.d. for each group. Original magnification: × 200; scale bar, 200 μm.

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