Figure 5: Pericyte-specific deletion of Tie2 enhances tumour growth. | Nature Communications

Figure 5: Pericyte-specific deletion of Tie2 enhances tumour growth.

From: Pericyte-expressed Tie2 controls angiogenesis and vessel maturation

Figure 5

(a) Representative images of B16 tumours grown subcutaneously for 14 days in WT and Tie2PEKO mice. (b) Quantification of tumour weight of B16 tumours grown subcutaneously for 14 days in WT and Tie2PEKO mice. (c) Representative images of LLC tumours grown subcutaneously for 12 days in WT and Tie2PEKO mice. (d) Quantification of tumour weight of LLC tumours grown subcutaneously for 12 days in WT and Tie2PEKO mice. (e) Representative images from bioluminescence analysis 10 days after subcutaneous injection of B16 cells in WT and Tie2PEKO mice. (f) Quantitative bioluminescent analysis (linear) of B16 tumour burden in WT and Tie2PEKO mice. (g) Quantitative bioluminescent analysis (log-transformed) of B16 tumour burden in WT and Tie2PEKO mice. Scale bars: 5 mm (a,c). Data are shown as mean±s.d. Statistics were performed using Student’s t-test.*P<0.05, **P<0.01.

Back to article page