Figure 3 : Feasibility of strong coupling in Aspergillus niger, Corynebacterium glutamicum and Synechocystis species PCC 6803.

From: Growth-coupled overproduction is feasible for almost all metabolites in five major production organisms

Figure 3

Percentage of substrate-producible organic metabolites from A. niger, C. glutamicum and Synechocystis species PCC 6803 for which feasibility of strong coupling can be proven, depending on the minimum yield level. For the practically obligate aerobes A. niger and C. glutamicum aerobic growth on glucose was considered while photoautotrophic metabolism was assumed for Synechocystis. Statistics for the cMCS sizes and MILP computation time are shown in the table.