Table 1: Association between polygenic risk scores and number of children.

From: Reproductive fitness and genetic risk of psychiatric disorders in the general population

 Total populationMalesFemales
Polygenic scoreP valueBeta (CI)P valueBeta (CI)P valueBeta (CI)
ADHD0.0020.15 (0.05, 0.25)0.1700.09 (−0.04, 0.24)0.0020.20 (0.07, 0.33)
Autism0.002−0.25 (−0.41, −0.09)0.003−0.36 (−0.59, −0.12)0.130−0.16 (−0.38, 0.05)
Bipolar disorder0.740−0.005 (−0.03, 0.02)0.5000.01 (−0.02, −0.05)0.310−0.02 (−0.05, 0.01)
Major depression0.1700.04 (−0.01, 0.11)0.6500.02 (−0.07, 0.12)0.0940.07 (−0.01, 0.16)
Schizophrenia0.1600.006 (−0.002, 0.01)0.5300.004 (−0.008, 0.02)0.1700.007 (−0.003, 0.02)
  1. In total, ten tests on number of children were performed; thus the significance threshold is P<0.005.
  2. CI—95% confidence interval