Figure 1 : Overview of somatic mutations in thyroid tissues.

From: The genetic landscape of benign thyroid nodules revealed by whole exome and transcriptome sequencing

Figure 1

(a) Sampling schematic: Tissue samples were obtained from the thyroids of patients with or without PTC (>2 years follow-up). Sample Groups TB: benign nodule with concurrent PTC; SB: simple benign nodule without concurrent PTC. Normal tissues were at least 2 cm distant from the lesion foci. (b) Comparison of number of somatic mutations in PTCs, benign nodule and normal thyroid. Non-synonymous mutations included missense, stopgain SNV and indels. Mean±s.d., **P<0.01 Wilcoxon signed-rank test. (c) Comparison of number of somatic mutations in benign nodules from TB and SB patients, as well as normal thyroid from TB and SB patients. Mean±s.d., *P<0.05 by Wilcoxon signed-rank test.