Table 1 The body characteristics and serum protein concentrations of wild mice and their comparison to laboratory mice.

From: The comparative immunology of wild and laboratory mice, Mus musculus domesticus

Parameter Laboratory Wild  
Female Male Female versus Male Female Male Female versus Male Lab. versus Wild
Age (weeks)     7.2 (1.4–39.5; 80) 6.2 (1.0–20.9; 99) F1, 178=2.426  
Body length (mm)     67 (50–80; 81) 70 (48–86; 100) F1, 180=3.448  
Body mass (g) 20.5 (14.1–40.4; 37) 25.75 (19–32; 24) F1, 60=8.35** 12.9 (3.3–24.9; 81) 13.9 (4.7–20.4; 100) F1, 180=0.204 F1, 241=193.2***
Spleen mass (mg) 82 (48–132; 38) 76 (53–112; 24) U=408 25 (2–200; 78) 24 (4–644; 99) U=3891 U=10575***
Viable spleen cells (millions) 101 (0.43–299; 38) 119 (2.66–204; 24) U=575 20.5 (1.40–78.20; 64) 20.6 (4.6–86.2; 83) U=2718 U=8575***
Spleen mass: body mass ratio 0.0039 (0.0025–0.0053; 36) 0.0031 (0.0022–0.0041; 24) F1, 59=22.74*** 0.0020 (0.0030–0.0044; 78) 0.0020 (0.0004–0.0081; 97) F1, 174=0.005 F1, 234=116.67***
Serum IgG (μg ml−1) 358 (9–13326; 39) 282 (47–1912; 24) U=376 6889 (221–35784; 79) 5716 (200–35642; 96) U=3374 U=517***
Serum IgE (μg ml−1) 0.42 (0.01–15.21; 34) 0.33 (0.03–0.69; 17) U=193 132 (8–753; 79) 81 (1–832; 96) U=2685*** H=123.1***, LF<WF***, LF<WM***, LM<WF***, LM<WM***
Faecal IgA (μg g−1) 248 (170–379; 7) 163 (130–283; 5) U=7 199 (5–1168; 45) 268 (2–1178; 64) U=1534 U=621
SAP (μg ml−1) 1.29 (0.49–2.58; 33) 0.77 (0.30–1.96; 17) U=101*** 2.06 (0.11–6.43; 78) 1.68 (0.14–5.43; 96) U=3225 H=19.8***, LM<WF***, LM<WM**
Haptoglobin (μg ml−1) 0.505 (0.15–315; 40) 0.54 (0.54–424; 23) U=749*** 4.87 (0.36–1190; 78) 5.34 (0.48–571; 96) U=3630 H=56.5***, LF<WF***, LF<WM***
AAT (μg ml−1) 248 (4–488; 37) 286 (26–456; 19) U=436 272 (2–596; 77) 263 (3–748; 95) U=3631 U=4621
  1. The table shows the body characteristics and serum protein concentrations for wild and laboratory mice, shown as medians (range; n). Statistical results show comparisons between sex within animal source (that is, laboratory or wild mice), and between animal source. Where there exists a significant difference between sex, mice were grouped by sex and animal source as: laboratory female, laboratory male, wild female and wild male (LF, LM, WF, WM, respectively), with Kruskal–Wallis H-tests (and post hoc, Dunn–Bonferonni, pairwise comparisons) conducted with significant differences reported. Where data were normal (that is, body length, body mass and spleen mass: body mass ratio) or could be transformed to normal (log10 transformation of age; untransformed data shown), the results of univariate GLMs are reported. All non-normal data were analysed by Mann–Whitney U-tests, unless stated otherwise. Asterisks denote significant differences as *P<0.05, **P<0.01, ***P<0.001.