Figure 1 : Stereo view of the vertical channel composition of M-PPases.

From: Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism

Figure 1

Structural overview of an M-PPase:IDP complex, showing the various sub-structures in the active site: the hydrolytic centre, coupling funnel, ion gate and exit channel. Helices 5, 9, 10 and 15 have been removed for clarity.