Bar plots show mean connectivity values between networks for early and late practice in both samples. Asterisks indicate that decreases across practice in the learning sample (N=70) were significantly larger than in the control sample (N=67), with significance levels (**) for Bonferroni correction P<0.05 and (*) indicating FDR correction P<0.05, using two-sided two-sample t-tests. Black lines represent 95% confidence intervals. P values and t-values for all 55 between/within-network tests can be found in Supplementary Table 2. Brain images show edge-wise connectivity changes from early to late practice in the learning sample. Edge colours represent z-transformed correlation coefficient values. For clarity, edges with positive values are not shown. For 3D visualization, see also online Supplementary Video Material, videos 7–12. (a) Mean connectivity change between the FPN and DAN. (b–f) Mean connectivity changes between the DMN and task-related networks.