Table 4: Dissociation constants of T-STAR QUA1-KH and STAR domains and Sam68 QUA1-KH wild type (WT) and Y141E or Y241E mutants to RNAs containing two UAAA-binding sites separated by a poly-C linker.

From: Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68

Kd (μM)T-STARSam68
 STARQUA1-KHQUA1-KH
 WTY141EWTY141EWTY241E
UAAACCC7.06.87.910.950.027.1
UAAA-C5-UAAA5.95.15.55.342.74.6
UAAA-C10-UAAA7.04.98.64.437.33.9
UAAA-C15-UAAA6.74.76.84.726.34.0
UAAA-C20-UAAA2.15.72.45.18.44.8
UAAA-C25-UAAA1.45.21.86.24.05.5
UAAA-C30-UAAA1.76.72.06.05.07.5