Cell-surface carbohydrates are synthesized in a step-wise fashion, yielding products with unique capping structures. A recent study has shown that carbohydrates at the cell surface can be further remodeled by an endogenous glycosidase to alter the carbohydrate structure, thus generating a new function.
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Katie Ris-Vicari
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Fukuda, M., Bao, X. Seeing cellular sialidase transform sugars. Nat Chem Biol 4, 721–722 (2008). https://doi.org/10.1038/nchembio1208-721
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DOI: https://doi.org/10.1038/nchembio1208-721
