Nitrite, a ubiquitous stable oxidation byproduct of nitric oxide (NO) metabolism, is now entering the pantheon of signaling biochemical molecules. Nitrite may have the unique properties of a blood and tissue NO reservoir activated by physiological and pathological hypoxia.
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Gladwin, M. Nitrite as an intrinsic signaling molecule. Nat Chem Biol 1, 245–246 (2005). https://doi.org/10.1038/nchembio1005-245
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DOI: https://doi.org/10.1038/nchembio1005-245
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