Transporter proteins mediate the import of nutrients and the export of toxins across biological membranes. A new crystal structure of a bacterial ABC transporter reveals an unexpected mechanism for transporter inhibition by its transported substrate.
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Gaudet, R. The ABCs of trans(porter) inhibition. Nat Chem Biol 4, 454–455 (2008). https://doi.org/10.1038/nchembio0808-454
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DOI: https://doi.org/10.1038/nchembio0808-454