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Open access chemical and clinical probes to support drug discovery


Drug discovery resources in academia and industry are not used efficiently, to the detriment of industry and society. Duplication could be reduced, and productivity could be increased, by performing basic biology and clinical proofs of concept within open access industry-academia partnerships. Chemical biologists could play a central role in this effort.

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The authors thank C. Arrowsmith, I. Benjamin, D. Dodds, S. Frye, B. Greenberg, J. Weigelt, H. Widmer, T. Yamada and R. Young for comments on the paper. A.M.E. and C.B. are supported by the Structural Genomics Consortium, which is a registered charity (number 1097737) that receives funds from the Canadian Institutes for Health Research, the Canadian Foundation for Innovation, Genome Canada through the Ontario Genomics Institute, GlaxoSmithKline, Karolinska Institutet, the Knut and Alice Wallenberg Foundation, the Ontario Innovation Trust, the Ontario Ministry for Research and Innovation, Merck & Co., Inc., the Novartis Research Foundation, the Swedish Agency for Innovation Systems, the Swedish Foundation for Strategic Research and the Wellcome Trust.

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Correspondence to Aled M Edwards.

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Edwards, A., Bountra, C., Kerr, D. et al. Open access chemical and clinical probes to support drug discovery. Nat Chem Biol 5, 436–440 (2009).

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