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Sugars synthesized in a snap

The chemical synthesis of natural oligosaccharides by sequentially stitching monosaccharides together remains a major challenge because of the complexity of carbohydrate structures. A recent paper reports a versatile technology for creating selectively protected synthetic intermediates, thus providing easy access to complex oligosaccharides.

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Figure 1: Strategies for selective protection of glucose hydroxyls with different protecting groups.


  1. 1

    Wang, C.-C. et al. Nature 446, 896–899 (2007).

    CAS  Article  Google Scholar 

  2. 2

    Wong, C.-H., Ye, X.-S. & Zhang, Z. J. Am. Chem. Soc. 120, 7137–7138 (1998).

    CAS  Article  Google Scholar 

  3. 3

    Huang, X., Huang, L., Wang, H. & Ye, X.-S. Angew. Chem. Int. Ed. 43, 5221–5224 (2004).

    CAS  Article  Google Scholar 

  4. 4

    Zhang, Z. et al. J. Am. Chem. Soc. 121, 734–753 (1999).

    CAS  Article  Google Scholar 

  5. 5

    Hummel, G. & Schmidt, R.R. Tetrahedron Lett. 38, 1173–1176 (1997).

    CAS  Article  Google Scholar 

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Wang, P. Sugars synthesized in a snap. Nat Chem Biol 3, 309–310 (2007).

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