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Wanting contact: how to pick up a channel

Nature Chemical Biology volume 2, pages 298–299 (2006)Cite this article

Because of their transmembrane nature, ion channels are notoriously difficult subjects for high-throughput screening approaches. A new method has been developed that provides a simple, elegant and rapid means for assaying channel function.

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Figure 1: Schematic of the transfer of an αHL pore from a bacterial colony to a synthetic bilayer as described by Holden et al.2.

Ann Thomson

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Authors and Affiliations

  1. the the Departments of Biochemistry and Biophysics and of Cellular and Molecular Pharmacology, Cardiovascular Research Institute, and the California Institute of Quantitative Biomedical Research at the University of California, San Francisco, San Francisco, 94143-2532, California, USA

    Daniel L Minor Jr

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  1. Daniel L Minor Jr
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Minor, D. Wanting contact: how to pick up a channel. Nat Chem Biol 2, 298–299 (2006). https://doi.org/10.1038/nchembio0606-298

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