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Glycome 'fingerprints' provide definitive clues to HIV origins

Nature Chemical Biology volume 5, pages 198–199 (2009)Cite this article

It is well known that HIV-1 deceives the host immune system and usurps host cell machinery to replicate, but it is not known how this viral particle is released from the cell. A recent glycan profiling technique revealed that the glycome signatures of HIV-1 and host cell microvesicles are almost identical, providing important support for the 'exosome' hypothesis of viral release.

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Figure 1: A total scheme of protein glycosylation.

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Authors and Affiliations

  1. Jun Hirabayashi is in the Research Center for Medical Glycomics, National Institute of Advanced Industrial Science and Technology, Umezono, Tsukuba, Ibaraki, Japan. jun-hirabayashi@aist.go.jp,

    Jun Hirabayashi

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  1. Jun Hirabayashi
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Hirabayashi, J. Glycome 'fingerprints' provide definitive clues to HIV origins. Nat Chem Biol 5, 198–199 (2009). https://doi.org/10.1038/nchembio0409-198

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  • DOI: https://doi.org/10.1038/nchembio0409-198

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