The zebrafish is a highly promising model system for vertebrate genetics study, but the temporal control of gene expression has remained underdeveloped. A new chemical genetic system using a small-molecule switch for protein synthesis promises to increase the usefulness of the zebrafish as a vertebrate model system.
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Chang, YT. Small-molecule switch for zebrafish gene expression. Nat Chem Biol 3, 135–136 (2007). https://doi.org/10.1038/nchembio0307-135
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DOI: https://doi.org/10.1038/nchembio0307-135
