The broad range of techniques used in chemical biology presents many challenges in reporting, translating and implementing experimental knowledge. By taking advantage of some readily available solutions and instituting some new approaches, it should be possible to more effectively disseminate technological advances.
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References
Min, D.H. et al. Nat. Biotechnol. 22, 717–723 (2004).
Ong, S.E. & Mann, M. Nat. Chem. Biol. 1, 252–262 (2005).
Aharoni, A. et al. Nat. Methods 3, 609–614 (2006).
Varadarajan, N. et al. Proc. Natl. Acad. Sci. USA 102, 6855–6860 (2005).
Griffiths, A.D. & Tawfik, D.S. Trends Biotechnol. 24, 395–402 (2006).
Zanghellini, A. et al. Protein Sci. 15, 2785–2794 (2006).
Blount, K.F. & Breaker, R.R. Nat. Biotechnol. 24, 1558–1564 (2006).
Tucker, B.J. & Breaker, R.R. Curr. Opin. Struct. Biol. 15, 342–348 (2005).
Ellington, A.D. & Szostak, J.W. Nature 346, 818–822 (1990).
Tuerk, C. & Gold, L. Science 249, 505–510 (1990).
Buskirk, A.R. et al. Chem. Biol. 11, 1157–1163 (2004).
Werstuck, G. & Green, M.R. Science 282, 296–298 (1998).
Lin, Q. et al. J. Am. Chem. Soc. 125, 612–613 (2003).
Schwimmer, L.J. et al. Proc. Natl. Acad. Sci. USA 101, 14707–14712 (2004).
Otey, C.R. et al. PLoS Biol. 4, e112 (2006).
Schmidt-Dannert, C. et al. Nat. Biotechnol. 18, 750–753 (2000).
Yoshikuni, Y. et al. Nature 440, 1078–1082 (2006).
Patnaik, R. et al. Nat. Biotechnol. 20, 707–712 (2002).
Martinson, B.C. et al. Nature 435, 737–738 (2005).
Leonard, N.J. Tetrahedron 53, 2325–2355 (1997).
Katz, J.S. & Martin, B.R. Res. Policy 26, 1–18 (1997).
Melin, G. Res. Policy 29, 31–40 (2000).
Sambrook, J. & Russell, D.W. Molecular Cloning: a Laboratory Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 2001).
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The author would like to thank M. Trani, V. Conticello and D. Lynn for helpful discussions and critical review of the manuscript.
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Lutz, S. Tools, tricks and trade secrets: the challenges of disseminating methodology. Nat Chem Biol 3, 128–130 (2007). https://doi.org/10.1038/nchembio0307-128
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DOI: https://doi.org/10.1038/nchembio0307-128
