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Fluorescent timers shine a light on protein trafficking

Nature Chemical Biology volume 5, pages 70–71 (2009)Cite this article

Monomeric fluorescent proteins that change their emission characteristics as they mature have been successfully used to study the spatial and temporal dynamics of lysosome-associated membrane protein type 2A. This methodology provides a new means of studying cellular events in a dynamic mode.

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Figure 1: Suggested mechanism of formation of the chromophore in the fluorescent timer proteins of Subach et al.3.

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Authors and Affiliations

  1. Emre Dikici and Sylvia Daunert are in the Department of Chemistry, Rose Street, University of Kentucky, Lexington, Kentucky 40506-0055, USA. daunert@uky.edu,

    Emre Dikici & Sylvia Daunert

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  1. Emre Dikici
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  2. Sylvia Daunert
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Dikici, E., Daunert, S. Fluorescent timers shine a light on protein trafficking. Nat Chem Biol 5, 70–71 (2009). https://doi.org/10.1038/nchembio0209-70

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