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A road map of cellular protein homeostasis

Nature Chemical Biology volume 5, pages 911 (2009) | Download Citation

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A powerful technology called global protein stability profiling allows rates of protein turnover to be determined for a substantial fraction of the human proteome in a single experiment. This approach sets the stage for systems-level analyses of the dynamics of the mammalian proteome.

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Affiliations

  1. Xiaolu L. Ang and J. Wade Harper are in the Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02120, USA.  wade_harper@hms.harvard.edu

    • Xiaolu L Ang
    •  & J Wade Harper

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DOI

https://doi.org/10.1038/nchembio0109-9

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