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The proteasome makes sense of mixed signals

Nature Chemical Biology volume 5, pages 34 (2009) | Download Citation

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Protein ubiquitination is an important degradative signal, yet not all ubiquitinated proteins are degraded. Recent results reveal insights into the proteasome's strategy for integrating biophysical signals when choosing substrates for degradation.

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Author information

Affiliations

  1. Thomas J. Wandless is in the Department of Chemical and Systems Biology, Stanford University, Clark Center, W350A, 318 Campus Drive, Stanford, California 94305-5441, USA.  wandless@stanford.edu

    • Thomas J Wandless

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DOI

https://doi.org/10.1038/nchembio0109-3

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