Protein ubiquitination is an important degradative signal, yet not all ubiquitinated proteins are degraded. Recent results reveal insights into the proteasome's strategy for integrating biophysical signals when choosing substrates for degradation.
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Wandless, T. The proteasome makes sense of mixed signals. Nat Chem Biol 5, 3–4 (2009). https://doi.org/10.1038/nchembio0109-3
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DOI: https://doi.org/10.1038/nchembio0109-3