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Nature Chemical Biology volume 2, pages 1415 (2006) | Download Citation

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A new small molecule inhibitor of TNF has an unexpected mechanism: it disrupts the trimeric structure of the protein.

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Author information

Affiliations

  1. Tim Clackson is at ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, Massachusetts 02139, USA. clackson@ariad.com

    • Tim Clackson

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DOI

https://doi.org/10.1038/nchembio0106-14

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