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Synthetic biology

Automated design of RNA devices

RNA molecules have diverse functional roles, including silencing genes, catalyzing biochemical reactions and sensing chemicals that control gene expression. Biologists have drawn from nature's toolbox to construct engineered RNA molecules with versatile capabilities and can now begin to automate the design of libraries of regulatory RNAs.

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Figure 1: Automating the design of RNA devices.

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Correspondence to Farren J Isaacs.

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Isaacs, F. Automated design of RNA devices. Nat Chem Biol 8, 413–415 (2012). https://doi.org/10.1038/nchembio.942

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