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Alternative DNA structures

G4 DNA in cells: itae missa est?

Application of a synthetic DNA G-quadruplex ligand as a genome-wide probe has provided evidence for G-quadruplex DNA clusters in human cells.

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Figure 1: Quadruplex ligands act at specific genomic clusters.


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Correspondence to Jean-Louis Mergny.

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The author declares no competing financial interests.

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Mergny, JL. G4 DNA in cells: itae missa est?. Nat Chem Biol 8, 225–226 (2012).

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