Amino acids not only are useful for protein synthesis but also act as regulators of gene expression. An elegant genome-wide approach now shows how binding of amino acids to transcription factors regulates an integrated network of amino acid metabolism to suit the physiological needs of bacterial cells.
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Avin-Wittenberg, T., Galili, G. Amino acid regulatory wisdom. Nat Chem Biol 8, 23–24 (2012). https://doi.org/10.1038/nchembio.743
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DOI: https://doi.org/10.1038/nchembio.743
