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Reaction design

Nature-inspired total synthesis

Nature Chemical Biology volume 7, pages 582583 (2011) | Download Citation

Nature's approach to biosynthesis often involves the rapid generation of advanced, enantiopure intermediates from simple starting materials. A new, highly efficient strategy adapts this approach, using organocascade catalysis to quickly construct a key intermediate that can be converted into several complex natural products.

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Author information

Affiliations

  1. Laura Furst and Corey R. J. Stephenson are in the Department of Chemistry, Boston University, Boston, Massachusetts, USA.

    • Laura Furst
    •  & Corey R J Stephenson

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Corey R J Stephenson.

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DOI

https://doi.org/10.1038/nchembio.637

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