Nature's approach to biosynthesis often involves the rapid generation of advanced, enantiopure intermediates from simple starting materials. A new, highly efficient strategy adapts this approach, using organocascade catalysis to quickly construct a key intermediate that can be converted into several complex natural products.
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Furst, L., Stephenson, C. Nature-inspired total synthesis. Nat Chem Biol 7, 582–583 (2011). https://doi.org/10.1038/nchembio.637
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DOI: https://doi.org/10.1038/nchembio.637
