A unique heterotrimeric assembly of individually inactive paralogs, two of which are also involved in regulating phosphatase activity, creates one of the key enzymes of coenzyme A biosynthesis in yeast, pointing to the possibility of a previously undescribed cross-talk between metabolic and signaling pathways.
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Osterman, A. Genomic variations on a CoA biosynthetic theme. Nat Chem Biol 5, 871–872 (2009). https://doi.org/10.1038/nchembio.267
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DOI: https://doi.org/10.1038/nchembio.267