Commentary | Published:

The ABCs of PTMs

Nature Chemical Biology volume 14, pages 188192 (2018) | Download Citation

Post-translational modifications (PTMs) are ubiquitous in all forms of life and often modulate critical protein functions. Recent chemical and biological advances have finally enabled scientists to precisely modify proteins at physiologically relevant positions, ushering in a new era of protein studies.

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Acknowledgements

K.W.B. acknowledges support from the NSF (DGE-1122492), and J.R. is supported by the NIH (R01GM125951; R01GM117230; P01DK017433; U54CA209992).

Author information

Affiliations

  1. Karl W. Barber and Jesse Rinehart are in the Department of Cellular and Molecular Physiology and the Systems Biology Institute, Yale University, West Haven, Connecticut, USA.

    • Karl W Barber
    •  & Jesse Rinehart

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The authors declare no competing financial interests.

Corresponding author

Correspondence to Jesse Rinehart.

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DOI

https://doi.org/10.1038/nchembio.2572

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