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RNA structure: A LASER-focused view into cells

Nature Chemical Biology volume 14, pages 200201 (2018) | Download Citation

RNA structure is irrevocably linked to function. A new method, termed 'LASER', utilizes a light-activated chemical probe to query RNA tertiary structure and illuminate RNA–protein interactions in the living cell.

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Author information

Affiliations

  1. Philip Bevilacqua is in the Department of Chemistry and the Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.

    • Philip C Bevilacqua
  2. Sarah Assmann is in the Department of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.

    • Sarah M Assmann

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Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Philip C Bevilacqua or Sarah M Assmann.

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DOI

https://doi.org/10.1038/nchembio.2570