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RNA imaging

A tale of two G-quadruplexes

Nature Chemical Biology volume 13, pages 11401141 (2017) | Download Citation

In contrast to proteins, no intrinsically fluorescent RNA is known to exist in nature. In this issue, a new, red-shifted aptamer–fluorophore complex for RNA imaging that has enhanced photostability is described. The crystal structure of this complex reveals a novel form of RNA small-molecule recognition.

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Author information

Affiliations

  1. Aaron E. Engelhart is at the Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA.

    • Aaron E Engelhart

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The author declares no competing financial interests.

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Correspondence to Aaron E Engelhart.

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DOI

https://doi.org/10.1038/nchembio.2492

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