New approaches allow tight control over Cas9 activity using chemical induction. These studies expand the ability to rapidly induce and suppress Cas9-mediated nuclease activity and conditionally modulate the multiplex regulation of endogenous gene expression.
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Hilton, I., Gersbach, C. Chemical control for CRISPR editing. Nat Chem Biol 13, 2–3 (2017). https://doi.org/10.1038/nchembio.2243
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DOI: https://doi.org/10.1038/nchembio.2243
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