Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Motor proteins

Kinesin's gait captured

Kinesin is a motor protein that drives intracellular transport by stepping along microtubules in a hand-over-hand manner. Advanced dark-field microscopy has made it possible to capture the gait of this motor with unprecedented resolution.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Get just this article for as long as you need it


Prices may be subject to local taxes which are calculated during checkout

Figure 1: The gate of Kinesin-1 captured.


  1. Isojima, H. et al. Nat. Chem. Biol. 10.1038/nchembio.2028 (29 February 2016).

  2. Hirokawa, N., Noda, Y., Tanaka, Y. & Niwa, S. Nat. Rev. Mol. Cell Biol. 10, 682–696 (2009).

    Article  CAS  Google Scholar 

  3. Schnitzer, M.J. & Block, S.M. Nature 388, 386–390 (1997).

    Article  CAS  Google Scholar 

  4. Vale, R.D. & Milligan, R.A. Science 288, 88–95 (2000).

    Article  CAS  Google Scholar 

  5. Yildiz, A., Tomishige, M., Vale, R.D. & Selvin, P.R. Science 303, 676–678 (2004).

    CAS  Google Scholar 

  6. Andreasson, J.O. et al. eLife published online, 10.7554/eLife.07403 (22 April 2015).

  7. Mori, T., Vale, R.D. & Tomishige, M. Nature 450, 750–754 (2007).

    Article  CAS  Google Scholar 

  8. Verbrugge, S., Lansky, Z. & Peterman, E.J. Proc. Natl. Acad. Sci. USA 106, 17741–17746 (2009).

    Article  CAS  Google Scholar 

  9. Mickolajczyk, K.J. et al. Proc. Natl. Acad. Sci. USA 112, E7186–E7193 (2015).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Erwin J G Peterman.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Peterman, E. Kinesin's gait captured. Nat Chem Biol 12, 206–207 (2016).

Download citation

  • Published:

  • Issue Date:

  • DOI:


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing