Cytosolic proteins can be modified cotranslationally by the installation of O-GlcNAc groups onto serine and threonine residues. This modification suppresses cotranslational ubiquitination and stabilizes proteins against proteasomal degradation.
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Powers, E. An O-GlcNAc stamp of approval. Nat Chem Biol 11, 307–308 (2015). https://doi.org/10.1038/nchembio.1777
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DOI: https://doi.org/10.1038/nchembio.1777
