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Metals

Setting a trap for copper

In the assembly of metalloenzymes, the matching of metals and proteins must occur with absolute precision. When zinc-starved, Chlamydomonas maintains its balance of metals by sequestering copper in electron-dense traps for metals, thus preventing mishaps in protein metallation.

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Figure 1: Trapping copper under conditions of zinc starvation stress.

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Correspondence to Valeria Culotta.

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Culotta, V. Setting a trap for copper. Nat Chem Biol 10, 986–987 (2014). https://doi.org/10.1038/nchembio.1686

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