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Panning for phosphohistidine

Elusive pan-phosphohistidine (pHis) antibodies have been generated using a hydrolytically stable triazolyl-phosphonate hapten, promising to substantially accelerate efforts to better understand the role of pHis in biology.

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Figure 1: Panning for phosphohistidine just got much easier.

Katie Vicari

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Correspondence to Matthew J Piggott or Paul V Attwood.

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Piggott, M., Attwood, P. Panning for phosphohistidine. Nat Chem Biol 9, 411–412 (2013). https://doi.org/10.1038/nchembio.1273

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