Physiologically relevant ligands for mammalian odorant receptors have been elusive. A mouse odorant receptor–based bioassay has now been used to guide purification and identification of a natural ligand that mediates attraction of female mice to male urine.
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Luetje, C. Chemical courtship in mice. Nat Chem Biol 9, 140–141 (2013). https://doi.org/10.1038/nchembio.1180
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DOI: https://doi.org/10.1038/nchembio.1180