Glycosyltransferases, enzymes that catalyze glycosidic bond formation, are one of the most important but least well-characterized protein families found in nature. A new label-free, high-throughput glycan array–based strategy enables rapid profiling of tens of thousands of potential glycosyltransferase reactions.
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Gildersleeve, J. Carb loading strategy is spot on. Nat Chem Biol 8, 741–742 (2012). https://doi.org/10.1038/nchembio.1049