Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Hydrocarbon synthesis

Ringing the chains

An unusual cyclization reaction to form alkylarenes — which are important chemical feedstocks — from alkanes is mediated by an iridium catalyst.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Traditional synthesis of alkylarenes and their uses.

References

  1. Smith, M. B. & March, J. in March's Advanced Organic Chemistry 1194–1215 (Wiley, 2007).

    Google Scholar 

  2. Chopade, P. & Louie, J. Adv. Synth. Catal. 348, 2307–2327 (2006).

    Article  CAS  Google Scholar 

  3. Parenty, A., Moreau, X. & Campagne, J. M. Chem. Rev. 106, 911–939 (2006).

    Article  CAS  Google Scholar 

  4. Fürstner, A. & Langemann, K. Synthesis 792–803 (1997).

  5. Smith, M. B. & March, J. in March's Advanced Organic Chemistry 705–717 (Wiley, 2007).

    Google Scholar 

  6. Sheehan, R. J. in Ullmann's Encyclopedia of Industrial Chemistry doi:10.1002/14356007.a26_193 (Wiley, 2000).

    Google Scholar 

  7. Lorz, P. M. et al. in Ullmann's Encyclopedia of Industrial Chemistry doi:10.1002/14356007.a20_181.pub2 (Wiley, 2000).

    Google Scholar 

  8. Ahuja, R. et al. Nature Chem. 3, 167–171 10.1038/nchem.946 (2011).

    Article  CAS  Google Scholar 

  9. Jensen, C. M. Chem. Commun. 2443–2449 (1999).

  10. Zhu, K. M., Achord, P. D., X. W. Zhang, X. W., Krogh-Jespersen, K. & Goldman, A. S. J. Am. Chem. Soc. 126, 13044–13053 (2004).

    Article  CAS  Google Scholar 

  11. Woodward, R. B. & Hoffmann R. Angew. Chem. Int. Ed. Engl. 8, 781–853 (1969).

    Article  CAS  Google Scholar 

  12. Huber, G. W., Chheda, J. N., Barrett, C. J. & Dumesic, J. A. Science 308, 1446–1450 (2005).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hartwig, J. Ringing the chains. Nature Chem 3, 99–101 (2011). https://doi.org/10.1038/nchem.978

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchem.978

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing